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ScoFBA:Flux Balance Analysis of the Genome Scale Metabolic Reaction Network of Streptomyces coelicolor.

This server allows Flux Balance Analysis computations on genome scale metabolic reaction network model of Streptomyces coelicolor described in:

Irina Borodina, Preben Krebben and Jens Nielsen. Genome-scale analysis of Streptomyces coelicolor A3(2) metabolism. Genome Research 15:820-829, 2005.
[Article] [Supplementary files at Genome Research]

The FBA software and web interface implemented by Andrzej M. Kierzek


Tools

Single FBA run Use this tool to compute maximal flux towards selected metabolite and corresponding metabolic flux distribution.

Flux variability analysis Use this tool to study metabolic state of the system by computation internal flux ranges consistent with maximal flux towards selected metabolite.

Reaction essentiality scan Use this tool to find reactions essential for production of selected metabolite.

Single gene knockout Use this tool to run essentiality prediction for a particular gene.